盐酸非索非那定 [153439-40-8]
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英文名:Fexofenadine hydrochloride
- 别名:非索芬那定盐酸盐 索那定盐酸盐
- CAS号:153439-40-8 分子式:C32H40CLNO4 分子量:538.12
P190798-5G 盐酸非索非那定 [153439-40-8] 98.0% 5G 6600.00
P190799-1G 盐酸非索非那定 [153439-40-8] 98.0% 1G 1850.00
P190799-1G 盐酸非索非那定 [153439-40-8] 98.0% 1G 1850.00
订货编号 | 商品名称 | 规格 | 包装 | 单价 | 促销价 | 会员价 | 数量 |
P190798-5G | 盐酸非索非那定 [153439-40-8] | 98.0% | 5G | 6600.00 | 6600.00 | 登录可见 |
P190798-5G 盐酸非索非那定 [153439-40-8] 98.0% 5G 6600.00
|
P190799-1G | 盐酸非索非那定 [153439-40-8] | 98.0% | 1G | 1850.00 | 1850.00 | 登录可见 |
P190799-1G 盐酸非索非那定 [153439-40-8] 98.0% 1G 1850.00
|
化学性质
熔点 148-150oC
质量标准
S.No.
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Test
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Specification
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RESULTS
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1.
|
Description | A White to off white powder | Off white powder |
2.
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Solubility | Soluble in Methanol | Complies |
3.
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Indemnification | IR spectrum concordant with reference standard | Complies |
4.
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Melting range | 192.0℃to200.0℃ | 192.8℃to194.0℃ |
5.
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Colour absorbance | Not more than 0.1 | 0.02 |
6.
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Sulphated ash | Not more than 0.2%w/w | 0.09%w/w |
7.
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Loss on drying | Not more than 0.5%w/w | 0.11%w/w |
8.
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Related substances by HPLC |
-TRS-1: Not more than 0.3%w/w | Not detectable |
-TRS-2: Not more than 0.3%w/w |
0.01%w/w` |
||
Meta Fexofenadine: Not more than 0.3%w/w | Not detectable | ||
Any other known impurity: Not more than 0.3%w/w | 0.06%w/w | ||
Any unknown impurity : Not more than0.1%w/w | 0.04%w/w | ||
Total Impurities : Not more than1.0%w/w | 0.30%w/w | ||
9.
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Organic Volatile Impurities | Ethylene Chloride : Not more than100ppm | Not detectable |
10.
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Assay on dried basis | 98.5%to101.0% | 99.52% |
11.
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Residual solvents | Isopropyl Alcohol : Not more than5000ppm | 1485ppm |
Ethyl acetate : Not more than4000ppm | 965ppm | ||
Isopropyl acetate : Not more than500ppm | 85ppm | ||
Methanol : Not more than100ppm | Not Detectable | ||
Acetone :Not more than100ppm | Not Detectable | ||
12.
|
Bulk density | Not less than 0.25gm/ml | 0.29gm/ml |
13.
|
Particle size |
Particles less than 25 microns:Not less than90% |
96.5% |
Particles less than 10 microns:Not less than50% |
88 |
危险性质
危险品标志 Xi
危险类别码 36/37/38
安全说明 26-36
用途及存储
医药中间体
密封干燥保存。